Apexx Log - Folate (L-5-MTHF / Quatrefolic®)

Apexx Log - Folate (L-5-MTHF / Quatrefolic®)

Category: Water-soluble vitamin 
Form Used in Apexx01: L-5-MTHF (Quatrefolic®) 
Dose per Serving: 400 µg 
Verification: Independent EU laboratory testing for identity, purity, stability 

What Folate Is 

Folate is the collective term for a group of water-soluble B-vitamins involved in one-carbon metabolism, an essential biochemical system supporting DNA synthesis, amino acid conversion, and cellular function. 

Most dietary folate must be converted into its active form, L-5-methyltetrahydrofolate (5-MTHF). However, conversion efficiency varies between individuals due to genetic differences in the MTHFR enzyme.

Using the active form bypasses that variability. 

Why Folate Is Included in Apexx01 

Folate plays a central role in foundational physiology and supports multiple EFSA-recognised functions. 

It is included because it contributes to: 

Folate is a structural ingredient. It interacts with other B-vitamins to support biochemical systems that operate quietly in the background every day. 

Why This Form: L-5-MTHF (Quatrefolic®) 

Quatrefolic® delivers folate in its bioactive methylated form, bypassing the need for enzymatic conversion. 

This form is used because: 

Quatrefolic® is the most predictable and verifiable form for a daily protocol. 

Why This Dose: 400 µg

The dose aligns with: 

This amount is sufficient to support normal physiological processes without exceeding necessary intake. 

EFSA-Recognised Nutritional Functions of Folate 

Folate contributes to: 

Authorised claims only. 

How Folate Works Inside the Full Formula 

Folate interacts with: 

These interactions help maintain biochemical stability. 
Folate supports foundational metabolism, not acute effects. 

Why It Belongs in a Complete Daily Formula 

A core daily protocol must support the systems that remain unseen, cellular turnover, methylation, amino acid conversion, and metabolic regulation. Folate sits at the center of those networks. 

It is essential for a formula designed for consistency and foundation. 

Verification & Testing 

Each lot of L-5-MTHF undergoes: 

Quatrefolic® batches are independently verified before production. 

Compliant Summary